Conference: Health-care Associated InfectionsDecember 11-12, 2008 QEII Conference Centre, London, UK Competition: Young Voices in Research for HealthThe Lancet, together with the Geneva-based Global Forum for Health Research, announces the winners of the 2008 essay competition. Read the six winning essays at The Lancet Global Health Network. |
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Age-related macular degeneration (AMD) is the main cause of blindness in 30·5 million people worldwide. According to a Comment, this devastating outcome might change in the near future because of remarkable research developments currently taking place, such as the finding in an Article that alterations in the SERPING1 gene are strongly associated with AMD. A Seminar gives a comprehensive overview of the disease, discussed in a podcast. |
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Malaria protection for under-fives
Article The Lancet (online Nov 18)
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Surgical interventions for basal-cell carcinoma
Article The Lancet Oncology (online Nov 17)
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HIV vaccine
Article The Lancet (online Nov 13)
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President-elect Barack Obama signaled what is being viewed as a strong commitment to health-care reform by choosing former Senate Majority Leader Tom Daschle to head the federal department of Health and Human Services.
The American College of Cardiology and American Heart Association have released the first guidelines for the treatment of adults with congenital heart disease. These guidelines are intended to support the care of the rising number of adults with repaired heart defects, by providing comprehensive clinical information on several heart defects and highlighting key issues to look for in follow-up.
Aid agencies in the Democratic Republic of Congo say malnutrition and communicable diseases are taking their toll on refugees as fighting between government and rebel forces continues. A massive effort is under way to ensure the supply of life-saving medicines to hundreds of thousands of people, but, according to WHO, the biggest challenge is identifying where, and for which health conditions, supplies are needed most.
Malaria still kills around 1 million people every year, many of them young children in sub-Saharan Africa. A safe and effective vaccine is urgently needed to control the disease. A large make-or-break clinical trial of the RTS,S candidate vaccine, involving around 16 000 children, is soon to be launched in seven African countries.
More This Week in Medicine:
| 1. | Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications
in patients with type 2 diabetes (UKPDS 33) Research (1998) Lancet 352 (9131), pp. 837-853
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| 2. | MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: A randomised placebo-controlled
trial Research (2002) Lancet 360 (9326), pp. 7-22
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| 3. | Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: Principal results of the
Hypertension Optimal Treatment (HOT) randomised trial Research (1998) Lancet 351 (9118), pp. 1755-1762
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| 4. | A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE) Research (1996) Lancet 348 (9038), pp. 1329-1339
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| 5. | Peginterferon alfa-2b plus ribavirin compared with interferonalfa-2b plus ribavirin for initial treatment of chronic hepatitis
C: A randomised trial Research (2001) Lancet 358 (9286), pp. 958-965
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| 1. | Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind,
placebo-controlled trial Research (2008) Lancet 372 (9645), pp. 1223-1230
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| 2. | Thrombolysis with alteplase 3-4·5 h after acute ischaemic stroke (SITS-ISTR): an observational study Research (2008) Lancet 372 (9646), pp. 1303-1309
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| 3. | China and global health Comment (2008) Lancet 372 (9648), pp. 1439-1441
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| 4. | Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled
trial Research (2008) Lancet 372 (9647), pp. 1385-1393
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| 5. | Childhood outcomes after prescription of antibiotics to pregnant women with preterm rupture of the membranes: 7-year follow-up
of the ORACLE I trial Research (2008) Lancet 372 (9646), pp. 1310-1318
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